Indiana University-Purdue University Indianapolis

School of Informatics at IUPUI

People
Jake Chen

Jake Yue Chen

Assistant Professor

E-mail
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Phone
317-278-7604
Office
719 Indiana Ave.
WK 190
Indianapolis, IN 46202-3103

Web

http://bio.informatics.iupui.edu

Other Titles

  • Assistant Professor, Computer Science

Education

Ph.D. Computer Science and Engineering, University of Minnesota (2001)
M.S. Computer Science and Engineering with supporting minor in Biochemistry, Molecular Biology, and Biophysics, University of Minnesota (1997)
B.S. Biochemistry and Molecular Biology, Peking University, China (1995)

Biography

Jake Chen has been conducting research and development in bioinformatics and computational biology since 1995. Prior to coming back to academia, in 2002-3, he was the head of computational proteomics at Myriad Proteomics, Inc. (now Prolexys Pharmaceuticals, Inc.), Salt Lake City, Utah, where he led a team of bioinformatics researchers and developers to process and study the "human protein interactome" data, a proprietary network map of human protein-protein interactions consisting more than 10,000 human proteins and 80,000 interactions from more than 1TB of collected raw data. In 1998-2002, he worked as a senior consultant and then a bioinformatics computer scientist at Affymetrix, Inc., Santa Clara, California, where he developed several gene/mRNA selection databases of more than 100GB in size, which resulted in the commercialization of human U95, mouse U74, and rat U34 GeneChip microarrays. In 1996-8, he was a research assistant and consultant to the Computational Biology Center of the University of Minnesota, where he developed algorithms and databases to analyze Expressed Sequence Tags from several plant genome sequencing projects in the US. He has given many scientific presentations at leading US biotech firms, research institutes, universities, ACM/IEEE local meetings, and national/international conferences.

Jake Chen is passionate about innovating collaborative interdisciplinary research that has high-impact potentials. Besides conducting research, he denotes time to several community-based non-profit professional organizations.

  • Session Chair Session on Systems Biology and Informatics. SCI 2004 Conference, Orlando, FL
  • Program Committee/Session Chair IEEE Computer Society CSB 2002-2004, Stanford, California
  • Track Co-chair ACM Symposium on Applied Computing, Bioinformatics Track (2004), Cypris
  • Founding Chair Bay Area Young Scientists Forum, www.baysf.org (2001-present)
  • Board Member Association of Chinese Bioinformaticians, www.acbix.org (2001-present)
  • Chinese Association of Science and Technology, Utah Chapter (2002-3)

Research Interests

  • Computational Systems Biology, especially knowledge discovery in functional genomics, proteomics, and pharmacogenomics.
  • High-performance database computing, including semantic knowledge interoperation, complex querying, and scientific data mining.
  • Bio-discovery informatics, which will bridge gaps among bioinformatics, chemical informatics, and biomedical informatics.

Research by Topic